Netflix has released the official trailer for Little Brother, a new comedy starring John Cena and Eric André as one of the most chaotic “brother” pairings imaginable.
Cena plays Rudd, a tightly wound real estate agent whose polished, carefully managed life looks almost too perfect from the outside. That changes when Marcus, played by André, suddenly reappears. Marcus is not Rudd’s actual sibling, but his long-lost “little brother” from a school mentorship program — and after a hospital mix-up, he comes crashing back into Rudd’s life with absolutely no respect for boundaries, order or basic adult stability.
The trailer leans heavily into the collision between Cena’s controlled, image-conscious character and André’s full-force chaos machine. It is a classic comedy setup: one man trying desperately to protect the life he has built, and another man turning every room, dinner, conversation and relationship into a disaster zone.
Michelle Monaghan stars as Deirdre, Rudd’s wife, who helps bring Marcus into their home despite the very obvious warning signs. Christopher Meloni also appears, alongside Ego Nwodim, Sherry Cola and Caleb Hearon, giving the film a strong comedy ensemble around the central Cena-André dynamic.
Directed by Matt Spicer, Little Brother looks like a broad, raunchy, socially uncomfortable comedy about what happens when a picture-perfect life meets the one person capable of ruining it in record time. The premise is absurd, but there is a sharp little idea underneath it: people work very hard to curate their homes, relationships and public image — and then one unpredictable human being can wreck the whole damn showroom.
Little Brother premieres on Netflix on June 26, 2026.
Video source: Netflix
